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Recovery Effect of Blending Oil on Skin Barrier Damaged by Atopic Dermatitis

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KMID : 0869520140200010057
¼­¿µ¹Ì ( Seo Young-Mi ) - ¿ø±¤º¸°Ç´ëÇб³ °£È£Çаú

Abstract

Purpose: The purpose of this study was to evaluate the effect of a mixture of ARL oils, Agastache rugosa, Rosemarinu officinalis, and Lavandula angustifolia on atopic dermatitis (AD) model on NC/Nga mice.

Methods: Twenty-four, 6 week-NC/Nga mice were assigned to a control group (C, n=8), an AD-induced group (E, n=8), and an ARL oil-treated group (E, n=8) that had two treatments per day for 6 days. Epidermis thickness, total amount of collagen and expression of TGF-¥â in the AD induced mice were measured.

Results: The ARL oil-treated group showed a significantly decreased epidermis thickness, and a greater amount of collagen and expression of TGF-¥â compared with the AD-induced group.

Conclusison: ARL oil may be a putative resources for care or treatment of AD in the view of nursing intervention.
KeyWords
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Atopic dermatitis, Essential oil, Skin
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ÇмúÁøÈïÀç´Ü(KCI)